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Lower back pain is not listed as a common or characteristic adverse effect in the FDA-approved prescribing information for semaglutide formulations (Ozempic, Wegovy, or Rybelsus)
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doi: 10.1093/jnci/djx259 12
Cardiovascular Response (Unique to the Triple Agonist) : Retatrutides glucagon component stimulates the sympathetic nervous system, leading to a transient increase in resting heart rate during the early stages of titration (peaking around week 24 at a few extra beats per minute before gradually declining back to baseline)
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