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In addition, G6PD deficiencies are associated with resistance to the malarial parasite, Plasmodium falciparum , among individuals of Mediterranean and African descent

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a low ratio decreases IL-12 secretion which favors a Th2 response pattern over Th1 (a condition typically associated with chronic inflammation), while an elevated ratio favors a Th1 response (Brundu et al., 2016

doi:10.1111/dom.12993

Current Neuropharmacology, 13 (1), 71-88