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Standard Initiation Protocol Beginning with 0.5 mg weekly allows the body to adjust to the medication with minimal side effects

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If switching from tirzepatide to retatrutide, start retatrutide at 2 mg regardless of your previous tirzepatide dose and titrate up on the standard schedule

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About half of the participants had a body mass index (BMI) of 30 or more, the medical definition of obesity

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