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In a 2021 study conducted by Maar et al., the importance of TB-500 in cardiac regeneration and repair was emphasized
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However, in human systems the outcome of boosting NAD+ is complex and likely involves numerous pathways, from enhanced activity of sirtuins (implicated in longevity and metabolic control) to improved DNA damage repair, all of which are areas of ongoing investigation
Uncommon but notable adverse effects include: Hypokalaemia (low potassium) can occur during initial treatment of severe megaloblastic anaemia, as rapid cell production consumes potassium
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