We then apply this knowledge to formulate criteria for therapeutic efficacy in PMS, beginning with the need for early treatment owing to the substantial neuropathology that is already present at the initial clinical presentation
Cyanocobalamin is the synthetic, stable form of B12 used in most oral supplements and cheaper compounded formulations
Finally, while we believe the collection of peripheral blood markers complimented our central measures, it would have been informative to measure additional redox proteins directly implicated in oxidative stress processes, including peripheral TBARS and MDA concentrations
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