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The semaglutide group achieved a mean BMI reduction of 16.1% compared with a 0.6% increase in the placebo arm (estimated treatment difference: 16.7 percentage points
10.1210/en.2011-0174 66 KapogiannisD.MustapicM.ShardellM
Adems, la combinacin de un anlogo de GLP-1 con glucagn puede tener beneficios adicionales en trminos de prdida de peso y proteccin cardiovascular
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86 In patients with T2D and high cardiovascular risk, semaglutide use has resulted in fewer serious cardiac and kidney disorders compared to placebo but is linked to worsening diabetic retinopathy, likely due to rapid glucose reduction
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