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However, operators must carefully control ozone dosing to avoid the formation of byproducts like bromate

Current Pharmaceutical Design, 24(18), 1972-1989

If the patient is suspected to be sensitive to cobalt or other components of cobalamin, an intradermal test dose is recommended.[12][15] Several laboratory tests should be performed prior to treatment with cyanocobalamin, including serum vitamin B12, folate, iron, hematocrit, and reticulocyte count

The abdomen offers the most surface area for rotation, but the thighs and upper arms also work well