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Phase 2 clinical trial data published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated mean body weight reductions of up to approximately 24% over 48 weeks in adults with obesity a notable finding, though long-term durability data and head-to-head comparisons with other treatments are not yet available

Chronic oscillating glucose challenges disarrange innate immune homeostasis to potentiate the variation of neutrophil-lymphocyte ratio in rats with or without hidden diabetes mellitus

What We Don't Know: No human clinical trials yet

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Furthermore, comprehending the interplay between ferroptosis and other cell death mechanisms, including apoptosis and necrosis, might provide novel insights into the etiology of OA and inform the formulation of more holistic treatment approaches