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As nocebo behavior can lead in several consequences, such as polypharmacy and worse disease outcomes, physicians need to recognize patients with risk factors for nocebo behavior and cautiously communicate biosimilars efficacy and safety, in order to prevent nocebo phenomena [179]
Non-negotiable targets: Protein: 80-100g daily minimum (prevents muscle loss during weight loss) Calories: Dont go below 1,200 (women) or 1,500 (men) despite suppressed appetite Fiber: 25-35g daily (prevents constipation, supports gut health) Healthy fats: 30-50g daily (prevents gallbladder issues during rapid weight loss) Meal structure moving forward: Still smaller frequent meals (5-6 per day)
This triple-agonist approach makes it one of the most promising treatments currently being studied for obesity and type 2 diabetes management
These cohorts were similar in terms of demographic and key clinical factors, despite disparities in the available sample sizes, providing confidence that the separation of these analyses did not impose selection bias on our study
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