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Wang B, Li Y, Wu N, Lan CQ
S-2P in the Janssen Ad26-vectored vaccine (Ad26.COV2.S) and in the Novavax protein-based vaccine (NVX-CoV2373) contains additional mutations at the S1S2 polybasic cleavage site from RRAR to SRAG or QQAQ to render it protease resistant, which helps to further stabilize the S protein in its pre-fusion conformation 96,97
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Depending on your plan, certain medications may not be covered or can require prior authorization (sometimes referred to as precertification) if similar alternative medications are available at a lower cost
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