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Remarkably, this favorable phenotype was accompanied by a concomitant reduction in the hepatic content of ceramides, SM, and sphinganine but resulted in an increased hepatic content of S1P (64)

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For contexts where rapid and reliable serum levels are essential, injection remains preferred

B., Constantin-Teodosiu, D., & Greenhaff, P

Subsequently, the mixture was centrifuged at 12,000 g , 4 C for 5 min, and the supernatants were collected for LC-MS