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The decelerating weight loss in months 6-12 does not indicate failing appetite suppression
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Quick Reference: Standard Protocol Standard protocol: 250 mcg of each peptide, subcutaneous on empty stomach, AM and/or PM
In PIONEER 8, duration of diabetes, body weight and total daily insulin dose appeared to be higher in patients receiving basal-bolus insulin than in those on the other insulin regimens
Who May Be Considered for Dual-Agent Therapy (Red Flags) Candidates for tirzepatide-phentermine combination are exceptionally rare and typically have failed monotherapy with documented weight loss plateaus despite dose optimization
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