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Current Insights into the Role of UV Radiation-Induced Oxidative Stress in Melanoma Pathogenesis

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When HMGB1 is released into the TME because of cancer cell death, it can stimulate the innate immune system by interacting with several pattern recognition receptors (Sims et al., 2010

In an evaluation of 10 patients, it was found that STS before and/or after chemotherapy reduced therapy-related weakness, fatigue and gastrointestinal side effects