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Guilford FT, Hope J
The anti-PCSK9 antibody Ab#2 was affinity matured by rational design using a structure homology model of the mAb in complex with human PCSK9 to generate the optimised version Ab#2.1, which should deliver robust PCSK9 suppression at lower doses than Ab#2
The gradual dose titration schedule outlined in the SmPC aims to minimise these effects
As the name suggests, it pairs kojic acid with turmeric, which together brighten skin and improve dark spots and hyperpigmentation
Molecular mechanism of substrate recognition by folate transporter SLC19A1
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