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The originally identified activity was called retinaldehyde reductase
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In SURMOUNT-1, the most common treatment-emergent adverse events were gastrointestinal: nausea (24.6-33.3% across doses vs 9.5% placebo), diarrhea (18.7-21.2%), vomiting (5.7-12.2%), and constipation (5.8-11.5%)
The maximum recommended dose of Lexapro (escitalopram) for treating Generalized Anxiety Disorder (GAD) in adults is 20 mg once per day
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