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Damase, T
Looking Ahead: What Are the Unanswered Questions
The glucagon receptor in retatrutide directly stimulates hepatic fat oxidation, creating a specific mechanism for liver fat reduction that dual agonists lack
For some patients with treatment-resistant NAFLD, the dual approach yields superior liver enzyme improvements and greater visceral fat reduction than semaglutide monotherapy alone
Whilst the heart rate increases observed were statistically significant, they were not associated with a higher rate of serious adverse cardiac events in the Phase 2 data
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