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Its mechanism of action involves the direct inhibition of the transcription factor NF-B, a central regulator of the inflammatory response
CREDENCE: significant victory for diabetic kidney disease
Once the oxidative threat has passed and the cellular redox balance is restored, specialized enzymes such as glutaredoxin (Grx) or thioredoxin (Trx) carefully remove the glutathione cap, returning the protein to its normal, functional state
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