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The possible metabolic modifications of all cellular components or the microenvironment affecting the metabolism, transcriptome, properties, and phenotype of the tumor have been clearly described

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Overall, the combination of these approaches (i.e., univariate analysis and Random Forest) leverages the strengths of both univariate and multivariate analyses, leading to a more robust and comprehensive understanding of the data

Its a reminder that lasting results come from a long-term strategy