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The FDA does not approve any of these compounds for human use, and the agency oversees unapproved injectables through its drug program
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Retatrutide is the best-known triple agonist fitting that description
Regulatory submissions in other markets (EU, UK, Japan) would follow on a similar or slightly delayed timeline
The STEP 1 trial published in the New England Journal of Medicine in 2021 showed 14.9% mean weight loss at 68 weeks
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