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Adding the second receptor improved weight loss from roughly 15% to 22.5% in clinical trials (Jastreboff et al., NEJM 2022)
Fortier M, Castellano CA, Croteau E, Langlois F, Bocti C, St-Pierre V, et al
Some reviews describe a broad range of experimental findings, but there remains a gap between promising research and established, FDA-approved clinical use
When a supplement is highly bioavailable, the body can use the ingredient efficiently rather than struggling to process large amounts of unabsorbed powder
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