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Placed side by side, the Tufts 2007-2017 benchmark, the Health Affairs analysis spanning FDA's 2015 diversity action plan, and the Nature Communications Medicine analysis of 2017-2023 trials collectively describe a decade and a half in which national policy attention increased sharply but measured Black and Hispanic enrollment did not meaningfully improve, and by some measures worsened after 2020 ( [49] )

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Weakened cohesion increases the risk of premature chromosome separation, leading to aneuploidy

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Trastuzumab and chemotherapy are even recommended for patients with very small, HER2-positive breast cancers