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2.2.2 Regulatory mechanisms of hypoxia on NSCs In 1992, Reynolds and colleagues successfully isolated NSCs from the striatum of adult mice, marking a new era in NSC research (R et al., 1992)

PPIs used beyond 12 months have been associated with increased risk of Clostridioides difficile infection, hypomagnesemia, vitamin B12 deficiency, and a small increase in hip fracture risk (Vaezi et al., Gastroenterology, 2017) [11]

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