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The evidence base consists primarily of preclinical studies in animal models, with limited clinical data in humans

intravenous TB-4 Phase 1 safety and pharmacokinetics, no dose-limiting or serious adverse events (Ann N Y Acad Sci 2010;1194:223229): NCT00743769 Centers for Disease Control and Prevention

Nasal Sprays: A less common option, sometimes used for neurological support and brain health

Tendon and Ligament Support : Preclinical studies investigate mechanisms that may influence structural repair in connective tissues under stress or injury