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Since aging and oxidative stress increase the risk of developing DE, CR is also considered to have a possible therapeutic potential for DE
Its half-life extends approximately 4-6 hours when administered subcutaneously, with peak plasma concentrations reached within 30-60 minutes
After propensity score matching, each cohort included 4,912 patients balanced for age, sex, race, BMI, diabetes, cardiovascular risk factors, and immunosuppressive medication use
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