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10.1016/j.mce.2007.10.007 34 VroniqueR.PatrickL.StphaneL
However, given the TMAO elevating effect of oral L-carnitine supplementation, whether or not L-carnitine is a reasonable therapy to reduce Lp(a) levels requires further long-term investigations with hard clinical endpoints such as AMI, stroke and mortality risks
,
For example, co-administration of L-carnitine and -lipoic acid did not improve insulin resistance but markedly ameliorated mitochondrial ultrastructure and reduced serum liver enzyme levels, suggesting a preferential correction of mitochondrial injury (32)
they do not establish a therapeutic effect, safety profile or approved injectable use in humans
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