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Twenty participants were randomized to Phase II to account for potential withdrawals
Ideal for autoimmune/histamine-prone patients and gut-skin axis issues (acne, rosacea, eczema)
Consequence: increased eumelanin synthesis documented in the B16-F10 and MNT-1 cell models
The thousands of anecdotal human reports suggest similar effects to animal studies, but formal human clinical trials remain lacking
Gastroenterology 143 , 765776.e763 (2012)
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