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A Practical Look at Titration Both medications follow a gradual dose-escalation schedule designed to minimise gastrointestinal side effects as your body adjusts

B12 is naturally available only in animal proteins, so people who eat vegetarian or vegan diets may not consume enough B12

Patient-specific factors include age (older adults have more fragile blood vessels and thinner skin), genetic predisposition to easy bruising, nutritional status, and underlying medical conditions affecting coagulation or vascular integrity

This can cause redness, itching, dryness, and thickened skin