Serious side effects While the majority of the reported side effects with retatrutide were mild to moderate in severity, clinical trials also recorded a small number of serious adverse events
Extreme side effects that may be experienced by a person include pancreatitis, kidney failure, and various cancers
The study examined genetic variants in the GLP1R gene across diverse populations, including 408,774 white British individuals, 50,314 white Europeans, 7,667 South Asians, 10,437 individuals of multiple ancestries, and 7,641 African-Caribbeans
14,15 Another meta-analysis of 93 clinical trials showed that GLP-1 RAs increased the risk of early-stage DR compared with placebo, with this effect being driven by albiglutide in particular
The simulated population consisted of adults with obesity or overweight, defined as a body mass index (BMI) of 30 kg/m or27 kg/m with at least one obesity-related complication