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doi:10.1093/cvr/cvac120 14

The first GLP-1 agonistsintended to treat T2Dcame onto the market almost two decades ago

The concurrent engagement of all three receptors is hypothesised to produce complementary metabolic effects in pre-clinical models: GLP-1R activation is associated with glucose regulation and appetite modulation, GIPR activation with potentiation of GLP-1mediated responses, and GcgR activation with energy expenditure and hepatic lipid metabolism in laboratory settings

GLP-1 Receptor Agonists and Ocular Outcomes: Metabolic Transition, Retinal Vulnerability, and Risk-Stratified Monitoring

You will need to talk to your insurance company to see if either of these medications will be covered