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Discontinuation rates in SURMOUNT-1 were 14% to 16% across dose groups, meaning most people tolerate the medication well enough to continue treatment
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This protocol can continue for about eight weeks , after which users are generally advised to take a break for eight to ten weeks to avoid potential complications from continuous use 1
00:13:12 Vickie Danaher However, no clinically relevant changes were observed for orforglipron when used with rosuvastatin or atorvastatin
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