From a litigation standpoint, the argument is clear: patients were never given the chance to make an informed decision, and many never would have agreed to use Ozempic had they been properly warned
Others are technically long-term but come with monitoring requirements, side effects, stopping rules or limits on how much weight patients could expect to lose
Recent safety reviews have examined whether semaglutide medicines, including Wegovy, may be associated with non-arteritic anterior ischemic optic neuropathy, or NAION
In terms of the overall program, symptoms usually peak during the titration phase
Patients were randomized to a 96-week course of metformin versus vitamin E versus placebo, and the primary outcome was ALT decrease, while histological improvement/NASH resolution was the secondary outcome