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129 In addition, the cholesterol homeostasis of cells is essential for the insulin secretion, as accumulated cholesterol in the plasma membrane resulting in impaired secretion via exocytosis, and reduced cholesterol in insulin granules making them enlarged, also resulting in secretory dysfunction
The first cohort comprised individuals who started and continued either a GLP-1 receptor agonist or DPP-4 inhibitor for the first time between January 1, 2007, and December 31, 2020
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Endothelial dysfunction in adipose triglyceride lipase deficiency
Typical genes, such as OCTN2 (encoded by SLC22A5) and /or BBD (encoded by BBOX1), regulated by PPAR play regulatory roles in the cellular fatty acid uptake, fatty acid activation, intracellular fatty acid transport, and -oxidation of mitochondrial and peroxisomal fatty acids (84)
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