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A 2025 review in Mayo Clinic Proceedings reports that 40% to 70% of patients on these medications experience gastrointestinal side effects, and that first-line management is dietary: smaller and more frequent meals, adequate hydration, and steering clear of high-fat and high-sugar foods
Lack of approval reflects insufficient human clinical trial data and incomplete evaluation of risks, dosing, and long-term effects
Furthermore, Vitamin C is a known tyrosinase inhibitor itself, meaning it provides a secondary layer of support for an even skin tone
Inject on the same day each week
No significant outliers were observed with principal components (PCA) analysis (Figure S3A)
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