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The principle under which GLP-1 RAs should be managed has shifted to strategy layeringrestoring calculator systems tailored to patients, rather than blanket medication cessation triggers that dominated prior models suspension approach
WuW-KPanyodSLiuP-YChenC-CKaoH-LChuangH-Let al
Moreover, GLP-1 RAs also exert beneficial roles on multiple organ systems in which the GLP-1 receptors exist, including the cardiovascular system
According to experiments by Zhu et al., TMAO improved the expression of adenosine diphosphate (ADP) and thrombin to enhance a release of Ca 2+ from intracellular calcium stores, causing platelet aggregation and enhancing thrombosis potential (88)
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