does tirzepatide affect bone density Do anti-obesity medications health? Weight Loss and Bone Health:

Taking tirzepatide instead

1,2 The only drug we have available and is guideline recommended for symptoms is contraindicated in people with heart failure, has no benefits beyond improvement in symptoms, and causes a lot of side effects, so overall its used in less than 10% of people, so we really have limited options to improve function in PAD, Bonaca said

Feb 1 2019;104(2):369-378

Giugliano, Insulin and glucagon-like peptide 1 receptor agonist combination therapy in type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials

In many medical trials, Tirzepatide has outperformed Semaglutide for the amount of weight loss it facilitates