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Di norma, in caso di piena funzionalit metabolica, una persona di 70 chilogrammi (kg) produce 11-34 milligrammi (mg) di carnitina al giorno (die), raggiungendo un contenuto corporeo totale di circa 20 g quasi interamente localizzato nelle cellule muscolari scheletriche

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Erastin, a ferroptosis inducer, binds to VDAC2 and VDAC3 on the outer mitochondrial membrane, inducing mitochondrial dysfunction and oxidant release, ultimately triggering ferroptosis in tumor cells

Animal models also show improved bile acid profiles, which also reduces fibrosis