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Yoon KH, Kang J, Kwon SC, Trautmann ME, Hompesch M, Stewart J, Sorli CH (2020) Pharmacokinetic and dose-finding studies on efpeglenatide in patients with type 2 diabetes
In the SUMMIT HFpEF trial, a 38% lower risk of cardiovascular death or worsening heart failure was reported, alongside changes in cardiometabolic and lipid markers
Mounjaro for Type 2 Diabetes: A New Era in Blood Sugar Control Although Mounjaro is now widely used for weight management, it was originally developed and approved for type 2 diabetes
Its almost always traded off against efficacy
The outcomes were (1) at-risk steatohepatitis defined as Fibroscan-AST (FAST) score 0.67, (2) significant or advanced fibrosis defined by liver stiffness measurement (LSM) 8.8 and 11.7 respectively, and (3) advanced fibrosis defined by AGILE3+ score 0.68
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