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They are especially important in the study of optimization problems where they are distinguished by a number of convenient properties
These include stress reduction, behavioral therapies, exercise, and medication
The background rate of headache in the general population is substantialtension-type headaches affect up to 40% of adults annuallymaking it challenging to definitively link every headache to medication use
doi:10.1111/j.1365-313X.2007.03280.x
Some patients and providers use 2-week or even weekly escalations to reach therapeutic dose faster
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