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(2) the specific CI inhibitor IACS-010759 was recently reported to promote neurotoxicity, making this an unattractive agent for combination therapy in CRC given the neurotoxicity long-recognized with oxaliplatin treatment 51
& Carneiro, G
It is beneficial to the functioning of the central and peripheral nervous system
Gut Microbes 14:2027853
As a result, peptide stabilization requires careful attention to solvent systems, pH, and packaging
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