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2 Effects of SSRIs on reproductive cytogenesis 2.1 Effects of SSRIs on male germ cells Several studies have found that fluoxetine disrupts the hypothalamuslobetestis axis, significantly decreasing the serum concentrations of luteinizing hormone (LH), follicle stimulating hormone (FSH), progesterone, and testosterone, while also affecting several sperm quality parameters, as evidenced by decreased sperm concentrations and viability, increased deoxyribonucleic acid (DNA) fragmentation, and lower reproductive organ weights (Ayala et al., 2018
Current laboratory, animal, and early clinical research is encouraging and has not identified a consistent pattern of serious adverse events
Each pen contains pharmaceutical-grade compounds with precise dosing mechanisms, eliminating the need for reconstitution and reducing handling errors
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