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Together, these two mechanisms explain why low-dose atropine can paradoxically enhance vagal effects and slow sinoatrial node firing before higher doses shift the balance toward the expected anticholinergic tachycardia
Combination therapies such as Qsymia or the generic phentermine plus topiramate regimen also use stepwise increases to ensure tolerability
However, these same mechanisms can lead to gastrointestinal adverse effects
(2025, June 25)
[Consulta: 20 maig 2008]
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