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(50 mg IM twice weekly slowed functional decline by ~43% in early-stage ALS.) Clinical safety of ultra-high-dose methylcobalamin in patients with amyotrophic lateral sclerosis: Open-label extension (long-term safety data)
Vitamin B-12 deficiency is not super common in the U.S
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Some patients feel as though they want more frequent injections, and occasionally we test levels to see if they are receiving adequate replacement, but Im not sure how strong the evidence is to support this. GPs should consider periodic vitamin B12 testing of higher-risk patients who take metformin, even if they dont display symptoms of deficiency, the UK medicines regulator said earlier this year
Needle Dead Space Dead space within the needle hub and shaft affects the dosage accuracy in B12 injections
