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(6,7) Both estimates are notably higher than the adult obesity projection of approximately 40%

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Thus, defined essentially by exclusion as a hereditary hemolytic anemia that is not hereditary spherocytosis (or without any other major aberration of red cell morphology), it is not at all surprising that hereditary nonspherocytic hemolytic anemia has proven to be extremely heterogeneous both in etiology and in clinical manifestations

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