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Nadeem D, Taye M, Still MD, et al

Semaglutide carries certain contraindications and may not be suitable for everyone

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Each patient begins with a comprehensive medical evaluation to determine clinically appropriate strategies based on metabolic, hormonal, and lifestyle factors

The agency warned that unapproved versions "do not undergo FDA's review for safety, effectiveness and quality before they are marketed" and called out vendors falsely labeling chemicals as "for research purposes only." Michaels argued that the surge in illegal sales is largely driven by people trying to lose "vanity pounds" quickly after taking inspiration from extreme body transformations in pop culture