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Each requires different reconstitution volumes and produces different concentrations
When an amylin analogue like cagrilintide is paired with a GLP-1/GIP receptor agonist, the complementary mechanisms appear to produce additive appetite suppression: cagrilintide slows gastric emptying through amylin receptor activation, while tirzepatide simultaneously boosts insulin secretion and reduces glucagon
Whilst gastrointestinal side effects such as nausea and diarrhoea are well documented, patients occasionally report changes in stool appearance, prompting questions about whether Ozempic causes dark stools
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