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It is administered through small subcutaneous injections
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Dog breeds that benefit most from cobalamin supplements are Giant Schnauzers, Chinese Shar-Peis, Border Collies, Beagles, and Australian Shepherds, as they have a genetic predisposition to selective cobalamin malabsorption
One study investigating the role of nutrition in DNA replication, DNA damage prevention, and DNA repair confirmed that folate and vitamin B12 are required for nucleotide synthesis and DNA replication, as well as the maintenance of DNA methylation and chromosome stability