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Overexpression of F3H in rice enhanced quercetin and kaempferol biosynthesis under salinity stress (Jan et al., 2021), while SIbHLH22 overexpression in tomato promotes flavonoid accumulation under drought and salinity stress, albeit with developmental trade-offs such as reduced plant height and smaller leaves (Waseem and Li, 2019)
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They may support functions such as memory, focus, mood regulation, and neuroprotection
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