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Interestingly, NLRP3 deficient PD murine models showed protection from PD, making it a desirable therapeutic target [15, 70]

Moreover, these drugs are often associated with side effects such as gastrointestinal distress, dizziness, and nausea, further limiting their long-term clinical utility ( 4.4 Socioeconomic burden and the need for cost-effective therapies Beyond its medical impact, AD imposes a substantial socioeconomic burden, affecting patients, caregivers, and healthcare systems

Widiger TA, Oltmanns JR

European journal of nutrition, 54(2), 251263