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Supplementary material The Supplementary Material for this article can be found online at: References 1 AkiyamaS.FukudaS.SteinbergJ

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Results of lifestyle modification promotion and reproductive/general health check for male partners of couples seeking conception

Figure 1 A metabolite set enrichment analysis made from the 31 metabolites significantly modulated by MTX confirmed the major impact of the drug on glycine and serine metabolism, the urea cycle, alanine metabolism, and arginine and proline metabolism ( Figure 1B )