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Whether patients will tolerate daily dosing and strict timing requirements, and whether they will continue treatment long enough to see meaningful results, are important considerations for individual treatment planning

For a non-dietary cause, maintenance is usually one injection every two to three months for life

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34 SGLT-2 inhibitors Since SGLT-2 activity accounts for the majority of glucose reabsorption in the kidney, inhibition of SGLT-2 effectively blocks the reabsorption of filtered glucose, leading to a pharmacologically augmented glucosuria

IGF-1 DES: Also available but potentially slightly less common in UK supplier inventories